Alcohol is among the most used psychoactive substances in Europe and its consumption is considered the fifth risk factor for the global burden of disease. Every day around 800 people in Europe die from causes attributable to alcohol consumption and in Italy on average there are 48. These are some of the data presented in the Istisan Report “ Epidemiology and alcohol-related monitoring in Italy and in the Regions. Evaluation of the National Alcohol Observatory on the impact of alcohol consumption for the purpose of implementing the activities of the National Alcohol and Health Plan. Report 2020 “, published by the ISS.